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Pancreas - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		160	140	146	173	167	155	157	150	1248
Crude rate		23.5	20.7	21.7	25.9	25.1	23.0	22.9	21.7	23.1 (21.8‑24.4)
Standardized rate	Italy 2001	17.4	15.1	15.2	18.3	16.6	15.7	16.5	15.4	16.3 (15.4‑17.2)
Standardized rate	Europe	11.0	9.5	9.0	11.5	9.7	9.7	10.7	9.4	10.1 (9.5‑10.7)
Standardized rate	World	7.0	6.0	5.6	7.4	6.0	6.0	6.9	6.0	6.4 (6.0‑6.8)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		138	131	123	146	138	138	127	135	1076
Crude rate		20.3	19.4	18.3	21.8	20.7	20.4	18.5	19.6	19.9 (18.7‑21.1)
Standardized rate	Italy 2001	14.7	14.1	13.0	15.5	13.8	13.9	13.1	13.5	13.9 (13.1‑14.8)
Standardized rate	Europe	8.8	8.6	8.0	9.6	8.3	8.3	8.2	8.1	8.5 (7.9‑9.0)
Standardized rate	World	5.4	5.3	5.1	6.1	5.2	5.1	5.2	5.1	5.3 (4.9‑5.7)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	84.5	93.4	85.5	84.7	83.1	88.5	79.4	87.7	85.3
Cito-histologically confirmed (%)	37.5	37.9	36.3	49.7	37.1	47.1	44.6	52.0	42.9
Death certificate only - DCO (%)	5.0	7.9	4.1	2.3	7.8	7.7	4.5	6.0	5.6

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	9.9	9.4	10.5	7.8	7.3	9.3
Mortality	8.2	7.9	9.4	7.3	6.7	8.4

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	218	35.2	224	35.6	442	35.4
Citological	34	5.5	59	9.4	93	7.5
Clinical	338	54.6	304	48.3	642	51.4
DCO	29	4.7	41	6.5	70	5.6

Table 6: More frequent morphologies

Morphology	N	%
Adenocarcinoma, NOS	174	61.5
Infiltrating duct carcinoma, NOS (C50._)	56	19.8
Carcinoma, NOS	19	6.7
Tumour cells, malignant	9	3.2
Neuroendocrine carcinoma, NOS	8	2.8
Mucinous adenocarcinoma	6	2.1

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	0.0	0.0
25-29	0.0	0.0
30-34	0.0	0.0
35-39	1.4	0.5
40-44	1.5	0.0
45-49	0.0	0.0
50-54	7.2	3.0
55-59	15.9	13.3
60-64	25.1	25.6
65-69	32.8	25.0
70-74	54.1	44.4
75-79	87.0	77.0
80-84	95.3	86.6
85+	133.0	115.1

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	8.8	11.0
2000	8.6	9.5
2001	8.0	9.0
2002	9.6	11.5
2003	8.3	9.7
2004	8.3	9.7
2005	8.2	10.7
2006	8.1	9.4

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	10.2	6.8	8.3	11.9	11.1	13.5
2-5	3.5	2.1	2.7	3.7	4.5	3.8
5-10	2.7	2.0	2.7	2.9	2.2	2.6
10-15	0.9	0.7	1.4	1.1	1.2	0.9
15-20	0.4	0.2	0.8	0.4	0.3	0.4
>20	0.3	0.1	0.3	0.2	0.5	0.3

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	9.6 (4.0‑15.2)
North West	9.2 (7.6‑11.0)
North Est	8.4 (7.0‑9.8)
Centre	9.6 (7.2‑12.4)
South	7.7 (5.6‑10.2)
Italy	8.5 (7.7‑9.5)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	43.70	19.60	14.20	13.20	12.10
45-59	100.00	31.10	16.10	8.80	5.80	4.90
60-74	100.00	13.50	6.10	4.50	4.10	3.60

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	21.7	19.1	23.6	25.4
2	9.4	7.7	10.9	15.5
3	5.6	4.3	8.9	8.1
4	4.3	3.3	7.3	6.3
5	4.1	3.3	6.7	4.5

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	22.4	24.2	21.7	20.5	22.9
Mortality	17.3	22.1	16.2	19	20.6

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	21.2	29.7
2	11.5	15.0
3	5.4	10.8
4	5.4	6.2
5	5.4	6.2