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Kidney and urinary tract - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		117	96	96	95	113	120	104	97	838
Crude rate		17.2	14.2	14.3	14.2	17.0	17.8	15.2	14.1	15.5 (14.4‑16.6)
Standardized rate	Italy 2001	13.6	10.9	11.2	10.9	12.8	13.5	11.6	10.2	11.8 (11.0‑12.7)
Standardized rate	Europe	10.0	7.6	8.3	7.7	9.3	9.6	8.3	6.9	8.4 (7.8‑9.1)
Standardized rate	World	7.2	5.4	6.0	5.4	6.8	6.9	5.6	4.8	6.0 (5.5‑6.6)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		51	38	43	31	37	39	42	41	322
Crude rate		7.5	5.6	6.4	4.6	5.6	5.8	6.1	5.9	5.9 (5.3‑6.6)
Standardized rate	Italy 2001	5.6	4.1	4.6	3.4	3.8	4.0	4.1	4.0	4.2 (3.8‑4.7)
Standardized rate	Europe	3.6	2.7	3.0	2.3	2.3	2.3	2.4	2.6	2.7 (2.3‑3.0)
Standardized rate	World	2.4	1.9	1.9	1.8	1.5	1.4	1.5	1.6	1.7 (1.5‑2.0)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	41.2	37.6	41.1	31.2	29.7	29.6	35.3	39.2	35.6
Cito-histologically confirmed (%)	72.7	79.2	79.2	82.1	85.0	80.8	84.6	80.4	80.4
Death certificate only - DCO (%)	4.3	1.0	4.2	0.0	0.9	1.7	1.0	5.2	2.3

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	8.5	6.8	9.5	8.9	5.3	8.4
Mortality	2.4	2.3	2.6	2.1	1.6	2.3

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	302	74.8	347	80.0	649	77.5
Citological	13	3.2	12	2.8	25	3.0
Clinical	79	19.6	66	15.2	145	17.3
DCO	10	2.5	9	2.1	19	2.3

Table 6: More frequent morphologies

Morphology	N	%
Renal cell carcinoma, NOS (C64.9)	156	43.5
Clear cell adenocarcinoma, NOS	65	18.1
Transitional cell carcinoma, NOS	43	12.0
Papillary transitional cell carcinoma (C67._)	27	7.5
Renal cell carcinoma, chromophobe type (C64.9)	25	7.0
Papillary carcinoma, NOS	8	2.2

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	2.4	0.0
5-9	1.1	0.0
10-14	1.1	0.0
15-19	0.0	0.0
20-24	1.0	0.0
25-29	0.6	0.0
30-34	2.8	0.0
35-39	2.3	0.5
40-44	4.0	0.5
45-49	4.7	1.2
50-54	13.2	1.8
55-59	15.9	3.2
60-64	14.6	4.2
65-69	27.6	7.3
70-74	44.4	12.0
75-79	53.1	20.6
80-84	54.6	32.9
85+	46.7	33.8

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	3.6	10.0
2000	2.7	7.6
2001	3.0	8.3
2002	2.3	7.7
2003	2.3	9.3
2004	2.3	9.6
2005	2.4	8.3
2006	2.6	6.9

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	21.5	10.5	24.1	25.1	21.4	25.3
2-5	23.6	12.5	23.0	28.9	23.2	27.6
5-10	29.2	15.6	29.8	30.2	34.2	35.1
10-15	19.6	10.1	22.0	24.9	18.4	21.5
15-20	11.2	6.1	11.9	12.8	11.4	12.4
>20	17.1	10.4	17.7	19.6	17.3	19.6

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	66.4 (61.8‑71.0)
North West	56.9 (49.4‑63.6)
North Est	52.3 (45.9‑58.3)
Centre	59.0 (46.6‑69.4)
South	60.9 (42.7‑75.0)
Italy	55.7 (51.5‑59.7)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	88.60	88.60	85.70	82.50	79.30
45-59	100.00	91.20	87.30	81.70	81.20	77.20
60-74	100.00	85.50	79.90	76.70	74.60	73.80
75+	100.00	68.80	59.10	55.80	54.30	54.30

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	78	82.1	77.8	82.3
2	73.2	74.1	69.8	76.4
3	68.6	69.7	67.2	73.2
4	65.7	67.5	65.8	72.3
5	64.9	65.5	65.3	72.3

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	16	19.6	14.3	13.4	14.1
Mortality	5.7	5.3	5.9	5.9	5.4

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	76.9	84.8
2	74.3	78.9
3	72.4	78.0
4	71.3	75.0
5	70.9	74.9